Publications

2012

Chang A, Dutch RE. Paramyxovirus fusion and entry: multiple paths to a common end. Viruses. 2012 Apr;4(4):613-36. Epub 2012 Apr 19. Review. PubMed PMID: 22590688; PubMed Central PMCID: PMC3347325.
Courtney SC, Scherbik SV, Stockman BM, and Brinton MA. West Nile Virus infections suppress early viral RNA synthesis and avoid inducing the cell stress granule response. J Virol 2012; 86(7): 3647-3657. PMCID: PMC3302502.
de Alwis AR, Smith SA, Olivarez NP, Messer WB, Hynh JP, Wahala WMPB, White LJ, Baric RS, Crowe JE Jr, de Silva AM. Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions. PNAS 2012; 109(19):7439-44. PMCID: PMC3358852.
Gonzalez RJ, Weening EH, Frothingham R, Sempowski GD, Miller VL. Bioluminescence imaging to track bacterial dissemination of Yersinia pestis using different routes of infection in mice. BMC Microbiol. 2012; 12: 147. PMCID: PMC3436865 .
Graham, R. L., Becker, M. M., Eckerle, L. D., Bolles, M., Denison, M. R., and Baric, R. S. 2012. A stably attenuated coronavirus vaccine platform with impaired replicase fidelity is effective in an aged, immunologically vulnerable animal model. Nature Med.. Epub Nov 11, 2012. PMCID: PMC3518599.
Haining, W.N. and B. Pulendran, (2012). “Identifying gnostic predictors of the vaccine response.” Curr Opin Immunol. 24(3): p. 332-6. PMCID: PMC3383371
Haley KP, Skaar EP. A battle for iron: host sequestration and Staphylococcus aureus acquisition. Microbes Infect 2012; 14(3): 217-27. PMCID: 22123296
Huynh, J., S. Li, B. Yount, A. Smith, L. Sturges, J. C. Olsen, J. Nagel, J. B. Johnson, S. Agnihothram, J. E. Gates, M. B. Frieman, R. S. Baric, and E. F. Donaldson. 2012. Evidence supporting a zoonotic origin of human coronavirus strain NL63. J Virol. Dec;86(23):12816-25. doi: 10.1128/JVI.00906-12. Epub 2012 Sep 19. PMCID: PMC Journal - In Process
Jones CL, Llewellyn AC, Napier BA, Sampson T, Schroeder M, Weiss DS. Subversion of host recognition and defense systems by Francisella. Microbiol Mol Biol Rev. 2012;76:383-404. Review. PMCID: PMC3372254.
Jones CL, Sampson TR, Nakaya HI, Pulendran B, Weiss DS. Repression of Bacterial Lipoprotein Production by F. novicida Facilitates Evasion of Innate Immune Recognition. Cell Microbiol. 2012 May 25. doi: 10.1111/j.1462-5822.2012.01816.x. [Epub ahead of print]. PMCID: PMC3443312.
Kovarova M, Hesker PR, Jania L, Nguyen M, Snouwaert JN, Xiang Z, Lommatzsch SE, Huang MT, Ting JP, Koller BH. NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice. J immunol 2012; 189(4): 2006-16. NIHMS388118.
Lei Y, Wen H, Yu Y, Taxman DJ, Zhang L, Widman DG, Swanson KV, Wen KW, Damania B, Moore CB, Giguere PM, Siderovski DP, Hiscott J, Razani B, Semenkovich CF, Chen X, Ting JP.The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy. Immunity. 2012; 36(6): 933-46. PMCID: PMC3397828.
Lenz JD, Temple BR, Miller VL. Evolution and virulence contributions of the autotransporter proteins YapJ and YapK of Y. pestis CO92 and their homologs in Y. pseudotuberculosis IP32953. Infect Immun 2012; 80(10): 3693-705. PMCID: PMC3457547
Le Sommer C, Barrows NJ, Bradrick SS, Pearson JL, Garcia-Blanco MA. (2012) G protein-coupled receptor kinase 2 promotes flaviviridae entry and replication. PLoS Negl Trop Dis. 2012 Sep;6(9):e1820. doi: 10.1371/journal.pntd.0001820. Epub 2012 Sep 13. PMCID: PMC3441407
Llewellyn AC, Zhao J, Song F, Parvathareddy J, Xu Q, Napier BA, Laroui H, Merlin D, Bina JE, Cotter PA, Miller MA, Raetz CRH, Weiss DS. NaxD is a deacetylase required for lipid A modification and Francisella pathogenesis. Mol. Microbiol. 2012; Sep 11. doi: 10.1111/mmi.12004. Epub ahead of print. PMCID: PMC Journal in Process.
LoVullo ED, Miller CN, Pavelka MS, Kawula TH. TetR-based gene regulation systems for Francisella tularensis. Appl Environ Microbiol. 2012; 78(19): 6883-9. PMID: 22820330.
Lu B, Nakamura T, Inouye K, Li J, Tang Y, Lundback P, Valdes-Ferrer SI, Olofsson PS, Kalb T, Roth J, Zou Y, Erlandsson-Harris H, Yang H, Ting JP, Wang H, Andersson U, Antoine DJ, Chavan SS, Hotamisligil GS, Tracey KJ. Novel role of PKR in inflammasome activation and HMGB1 release. Nature 2012; 488(7413): 670-4. PMID: 22801494.
Messer WB , Yount B , Hacker KE , Donaldson EF , Huynh JP , et al. (2012) Development and Characterization of a Reverse Genetic System for Studying Dengue Virus Serotype 3 Strain Variation and Neutralization. PLoS Negl Trop Dis 6(2): e1486. doi:10.1371/journal.pntd.0001486. PCMID: PMC3289595.
Napier BA, Meyer L, Bina JE, Miller MA, Sjostedt A, Weiss DS. 2012. A novel link between intraphagosomal biotin requirements and virulence in Francisella. 109:18084-9. PMCID: PMC Journal in Process
Miller MA, Stabenow JM, Parvathareddy J, Wodowski AJ, Fabrizio TP, Bina XR, Zalduondo L, Bina JE. Visualization of murine intranasal dosing efficiency using luminescent Francisella tularensis: effect of instillation volume and form of anesthesia. PLoS One. 2012;7(2):e31359. PMID: 22384012
Morris JG, Greenspan A, Howell K, Gargano LM, Mitchell J, Jones JL, Potter M, Isakov A, Woods C, Hughes JM. Southeastern Center for Emerging Biologic Threats Tabletop Exercise: Foodborne Toxoplasmosis Outbreak on College Campuses. Biosecur Bioterror 2012; 10(1). PMID: 22283568.
Napier BA and Weiss DS. A novel link between intraphagosomal biotin requirements and virulence in Francisella. Proc. Natl. Acad. Sci. U.S.A. 2012. 109:18084-9. PMCID: PMC Journal in Process.
Pegram HJ, Lee JC, Hayman EG, Imperato GH, Tedder TF, Sadelain M, Brentjens RJ. Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning. Blood 2012; 119:4133-4141. PMCID: PMC3359735.
Pierini R, Juruj C, Perret M, Jones CL, Mangeot P, Weiss DS, Henry T. AIM2/ASC triggers caspase-8-dependent apoptosis in Francisella-infected caspase-1-deficient macrophages. Cell Death Differ. 2012 19:1709-21 . PMCID: PMC3438500
Poe JC, Minard-Colin V, Kountikov EI, Tedder TF. A c-Myc and surface CD19 signaling amplification loop promotes B cell lymphoma development and progression in mice. J Immunol. 2012; 189(5): 2318-25. PMID: 22826319.
Poe JC, Tedder TF. CD22 and Siglec-G/10 in B cell function and tolerance. Trends Immunol. 2012; 33:413-420. PMCID: PMC3407281
Prestwood TR, May MM, Plummer EM, Morar MM, Yauch LE, , Shresta S. Trafficking and replication patterns reveal splenic macrophages as major targets of dengue virus in mice. J Virolol 2012; 86 (22);12138-47 PMCID: PMC3486461.
Prestwood TR, Morar MM, Zellweger RM, Miller R, May MM, Yauch LE, Lada SM, Shresta S. Interferon-y-receptor restricts systemic dengue virus replication and prevents paralysis in interferon-a/b receptor-deficient mice. J Virolol 2012: 86(23); 12561-70.
PMCID: PMC3497655
Price PA, Jin J, Goldman WE. Pulmonary infection by Yersinia pestis rapidly establishes a permissive environment for microbial proliferation. Proc Natl Acad Sci USA. 2012; 109(8): 3083-8. PMCID: PMC3286930.
Pulendran, B. and D. Artis, (2012). “New paradigms in type 2 immunity.” Science. 337(6093): p. 431-5. PMCID: PMC Journal – In Process
Purcell EB, McKee RM, McBride SM, Water CM, Tamayo R. Cyclic diguanylate inversely regulates motility and aggregation in Clostridium difficile. J Bacteriol 2012; 194(13): 3307-16. PMCID: PMC3434733
Reynoso CK, Miller MA, Bina JE, Gallivan J, Weiss DS. 2012. Riboswitch-mediated control of gene expression during intracellular Francisella infection. Molecul Biol PMCID: PMC Journal in Process
Saini D, Hopkins GW, Seay SA, Chen CJ, Perley CC, Click EM, Frothingham R. Ultra-low dose of mycobacterium tuberculosis aerosol creates partial infection in mice. Tuberculosis 2012; 92: 160-5. PMCID: PMC3288716.
Sampson TR, Liu X, Schroeder M, Weiss DS. Rapid killing of Acinetobacter baumannii by polymyxins is mediated by a hydroxyl radical death pathway. Antimicrob Agents Chemother. 2012: 56:5642-9. PMCID: PMC3486575
Schneider M, Zimmermann AG, Roberts RA, Zhang L, Swanson KV,Wen H, Davis BK, Allen IC, Holl EK, Ye Z, Rahman AH, Conti BJ, Eitas TK, Koller BH, Ting JP. The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-kappaB. Nat Immunol. 2012; 13(9): 823-31. PMCID: PMC Journal - In Process.
Segovia J, Sabbah A, Mgbemena V, Tsai SY, Chang TH, Berton MT, Morris IR, Allen IC, Ting JP, Bose S. TLR2/MyD88/NF-kappaB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection. PLoS One 2012; 7(1): e29695. PMCID: PMC3266238.
Smith SA, Zhou Y, Olivarez NP, Broadwater AH, de Silva A, Crowe JE. Persistence of circulating B memory cell clones with potential for dengue virus disease enhancement for decades following infection. J Virolol. 2012; 86(5): 2665-75. PMCID: PMC3302281.
Wahala W, Huang CY, Butrapet S, White LJ, de Silva A. Recombinant dengue type 2 viruses with altered E protein domain III epitopes are efficiently neutralized by human immune sera. J Virolol. 2012; 86(7): 4019-23. PMCID: PMC3302537.
Weiss DS. The Great Escape: microbiotal LPS takes a Toll on the liver. Cancer Prev Res. 2012; 5:1078-80. PMCID: PMC3439157.
Williams KL, Wahala W, Orozco S, de Silva A, Harris E. Antibodies targeting dengue virus envelope domain III are not required for serotype-specific protection or prevention of enhancement in vivo. Virology. 2012; 429(1): 12-20. NIHMSID: NIHMS367833.
Yoshizaki A, Miyagaki T, DiLillo DJ, Matsushita T, Horikawa M, Kountikov EI, Spolski R, Poe JC, Leonard WJ, Tedder TF. Regulatory B cells control T cell autoimmune disease through IL-21-dependent cognate interactions. Nature 2012; (In press).

2011

Davis BK, Wen H, Ting JP. The inflammasome NLRs in immunity, inflammation, and associated diseases. Annu Rev Immunol 2011; 29: 708-35. PMCID: 21219188.
Denison MR, Graham RL, Donaldson EF, Eckerle LD, Baric RS. Coronaviruses: an RNA proofreading machine regulates replication fidelity and diversity. RNA Biol. 2011:8(2): 270-9. PMCID: 21593585.
DiLillo DJ, Griffiths R, Seshan SV, Magor CM, Ruiz P, Coffman TM, Tedder TF. B lymphocytes differentially influence acute and chronic allograft rejection in mice. J Immunol 2011;186(4):2643-54. PMCID: 21248259.
Gargano LM, Gallagher PF, Freeman AS, Morris JG Jr, Temporado Cookson S, Greenwald I, et al. Academic consortia: untapped resources for preparedness, response, and recovery—examining the cholera outbreak in Haiti. Emerg Infect Dis [serial on the Internet]. 2011 Nov.
Hinchey J et al, and Lee S. Lysine auxotrophy combined with deletion of the secA2 gene results in a safe and highly immunogenic candidate live attenuated vaccine for tuberculosis. PLoS One. 2011; 6(1):e15857. PMCID: 21264335.
Iwata Y, Matsushita T, Horikawa M, DiLillo DJ, Yanaba K, Venturi GM, Szabolcs PM, Bernstein SH, Magro CM, Williams AD, Hall RP, StClair EW, Tedder TF. Characterization of a rare IL-10-competent B cell subset in man that parallels mouse regulatory B10 cells. Blood. 2011; 117(2):530-41. PMCID: 20962324.
Jayakar HR, Parvathareddy J, Fitzpatrick EA, Bina XR, Bina JE, Re F, Emery FD, Miller MA. A galU mutant of Francisella tularensis is attenuated for virulence in a murine pulmonary model of tularemia. BMC Microbiol. 2011 Aug 5;11:179. PMID: 21819572
Johnson JB, Aguilar HC, Lee B, Park GD. Interactions of human complement with virus particles containing the Nipah virus glycoproteins. J Virol 2011;85(12): 5940-8. PMCID: 21450814.
Jones CL and Weiss DS. TLR2 Signaling Contributes to Rapid Inflammasome Activation during F. novicida Infections. PLoS One. 2011; 6(6): e20609.
Kasturi SP, Skountzou I, Albrecht RA, Koutsonanos D, Hua T, Nakaya HI, Ravindran R, Stewart S, Alam M, Kwissa M, Villinger F, Murthy N, Steel J, Jacob J, Hogan RJ, Garcia-Sastre A, Compans R, Pulendran B. Programming the magnitude and persistence of antibody responses with innate immunity. Nature. 2011; 470 (7335):543-7. PMCID: 21350488.
Llewellyn AC, Jone CL, Napier BA, Bina JA, Weiss DS. Macrophage Replication Screen Identifies a Novel Francisella Hydroperoxide Resistance Protein Involved in Virulence. PLoS One. 2011; 6(9): e24201.
Matsushita T, Tedder TF. Identifying regulatory B cells (B10 cells) that produce IL-10. Methods Mol Biol. 2011; 677:99-111. PMCID: 20941605.
Morrison TE, Oko L, Montgomery SA, Whitmore AC, Lotstein AR, Gunn BM, Elmore SA, and Heise MT. A mouse model of Chikungunya virus-induced musculoskeletal inflammatory disease: evidence of arthritis, tenosynovitis, myositis, and persistence. Am J Pathol, 2011; 178(1):32-40. PMCID: 21224040.
Nakaya HI, Wrammert J, Lee EK, Racioppi L, Marei-Kunze S, Haining WN, Means AR, Kastuir SP, Kah N, Li G-M, McCausland M, Kancun V, Kokko KE, Li S, Elbein R, Mehta AK, Aderem A, Subbarao K, Ahmed R, Pulendran B. Systems biology of vaccination for seasonal influenza in humans. Nature Immunol 2011 (In press).
Perry ST, Buck MD, Lada SM, Schindler C, Shresta S. STAT2 Mediates Innate Immunity to Dengue Virus in the Absence of STAT1 via the Type I Interferon Receptor. PLoS Pathog 2011; 7(2): e1001297. PMCID: 21379341.
Popa A, Pager CT, Dutch RE. C-terminal tyrosine residues modulate the fusion activity of the Hendra virus fusion protein. Biochemistry 2011;50(6): 945-52. PMCID: 21175223.
Saini D, Hopkins GW, Chen C-J, Seay SE, Click EM, Hartings JM, Frothingham R. Sampling port for real time analysis of bioaerosols in whole body exposure system for animal aerosol model development. J Pharmacol Toxicol Meth 2011;63(2): 143-9. PMCID: 20849964.
Sheahan T, Whitmore A, Long K, Ferris M, Rockx B, Funkhouser W, Donaldson E, Gralinski L, Collier M, Heise M, Davis N, Johnston R, Baric RS. Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus. J Virol 2011;85(1): 217-30. PMCID: 20980507.

2010

Ait-Oufella H, Herbin O, Bouaziz J-D, Binder CJ, Uyttenhove C, Laurans L, Taleb S, Van Vré E, Esposito B, Vilar J, Sirvent J, Van Snick J, Tedgui A, Tedder TF, Mallat Z. B cell depletion reduces the development of atherosclerosis in mice. J Exp Med. 2010; 207:1579-1587. PMCID: 20603314.
Alderman TS, Frothingham R. Validation of non-traditional containment equipment. In: Richmond J, ed. Anthology of Biosafety XII: Managing Challenges for Safe Operations of BSL3/ABSL3 Facilities. Mundelein, IL: American Biological Safety Association, 2010. (In press.)
Alderman TS, Frothingham R, Sempowski GD. Validation of an animal isolation imaging chamber for use in animal biosafety Level-3 containment. Applied Biosafety. 2010; 15(2): 62-66.
Anzaldi LL and Skaar EP. Overcoming the heme paradox: Heme toxicity and tolerance in bacterial pathogens. Infection and Immunity. 2010;78(12): 4877-89. PCMID: 20679437.
Barrows NJ, Sommer CL, Garcia-Blanco MA, Pearson JL. Factors affecting reproducibility between genome-scale siRNA-based screens. J Biomol Screen. 2010 Aug;15(7):735-47. Epub 2010 Jul 12. PMID: 20625183
Beltramello M, Williams KL, Simmons C, Macagno A, Simonelli L, Quyen N, Sukupolvi-Petty S, Navarro-Sanchez E, Young P, de Silva AM, Rey FA, Varani L, Whitehead SS, Diamond MS, Harris E, Lanzavecchia A, and Sallusto F. The human immune response to dengue virus is dominated by highly cross-reactive antibodies endowed with both neutralizing and enhancing activity. Cell Host Microbe 2010. (In press.)
Bina XR, Miller MA, Bina JE. Construction of a bioluminescence reporter for Francisella tularensis. Plasmid. 2010; 64(3):156-61. PMCID: 20620161.
Clinton SR, Bina JE, Hatch TP, Whitt MA, Miller MA. Binding and activation of host plasminogen on the surface of Francisella tularensis. BMC Microbiol. 2010; 10: 76. PCMID: 20226053.
DiLillo DJ, Matsushita T, Tedder TF. B10 cells and regulatory B cells balance immune responses during inflammation, autoimmunity, and cancer. Ann N Y Acad Sci 2010;1183: 38-57. PCMID: 20146707.
Dutch RE. Entry and fusion of emerging paramyxoviruses. PLoS Pathog. 2010 Jun 24;6(6):e1000881. PMCID: 2891828.
Eckerle LD, Becker MM, Halpin RA, Li K, Venter E, Lu XT, Scherbakova S, Graham RL, Baric RS, Stockwell TB, Spiro DJ, and Denison MR. Infidelity of SARS-CoV nsp14-Exonuclease mutant virus replication is revealed by complete genome sequencing. PLoS Pathog 2010.6(5): e1000896. doi:10.1371/journal.ppat.1000896. PMCID: 2865531
Huang MT-H, Mortensen BL, Taxman DJ, Craven R, Taft-Benz S, Kijek T, Fuller JR, Davis BK, Allen IC, Brickey W, Gris D, Wen H-T, Kawula TH, Ting JP-Y. Deletion of ripA alleviates suppression of the inflamasome and MAPK by Francisella tularensis. J Immunol 2010; 185:5476-85. PMID: 20921527.
Kehl-Fie TE, Skaar EP. Nutritional immunity beyond iron: a role for manganese and zinc. Curr Opin Chem Biol 2010;14(2): 218-24. PMCID: 20015678.
Krause JC, Tumpey TM, Huffman CJ, McGraw PA, Pearce MB, Tsibane T, Hai R, Basler CF, Crowe JE, Jr. Naturally occurring human monoclonal antibodies neutralize both 1918 and 2009 pandemic influenza A (H1N1) viruses. J Virol 2010;84(6): 3127-30. PCMID: 20042511.
Manicassamy S, Reizis B, Ravindran R, Nakaya H, Salazar-Gonzalez RM, Wang Y-C, Pulendran B. Activation of b-Catenin in Dendritic Cells Regulates Immunity Versus Tolerance in the Intestine. Science 2010;329: 849-853. PCMID: 20705860.
Matsushita T, Horikawa M, Iwata Y, Tedder TF. Regulatory B cells (B10 cells) and regulatory T cells have independent roles in controlling EAE initiation and late-phase immunopathogenesis. J Immunol. 2010; 185:2240-2252. PMCID: 20624940.
McElvania Tekippe E, Allen IC, Hulseberg PD, Sullivan JT, McCann JR, Sandor M, Braunstein M, Ting JP. Granuloma Formation and Host Defense in Chronic Mycobacterium tuberculosis Infection Requires PYCARD/ASC but Not NLRP3 or Caspase-1. PLoS One. 2010 Aug 20;5(8). PMCID: 20808838.
McFadden G. Killing a killer: what next for smallpox? PLoS Pathog 2010;6(1): e1000727. PCMID: 20126444.
Mortensen BL, FullerJR, Taft-Benz S, Kijek TM, Miller CN, Huang MTH, Hall JD, and Kawula TH. The effects of the putative transcriptional regulator IclR on Francisella tularensis pathogenesis. Infection and Immunity. 2010; 78:5022-32. PMCID:20921140
Pulendran B, Li S, Nakaya HI. Systems Vaccinology. Immunity. 2010 Oct 29;33(4):516-29. Review. PMID: 21029962
Pulendran B, Tang H & Manicassamy S. Programming dendritic cells to induce TH2 and tolerogenic responses. Nature Immunology 2010;11(8):647-55. PCMID: 20644570.
Rehm KE, Connor RF, Jones GJ, Yimbu K, Roper RL. Vaccinia virus A35R inhibits MHC class II antigen presentation. Virology 2010;397(1): 176-86. PCMID: 19954808. (RL Roper funded in previous grant cycle)
Rehm KE, Jones GJ, Tripp AA, Metcalf MW, Roper RL. The poxvirus A35 protein is an immunoregulator. J Virol. 2010;84(1): 418-25. PMCID: 19828608. (RL Roper funded in previous grant cycle)
Sims A, Pyrc K, Dijkman R, Jebbink M, Long C, Deming D, Vabret A, Pickles R, van der Hoek L, Baric R. Culturing clinical isolates of human coronaviruses: HKU1 replication in human epithelial cell cultures. J Virol 2010 (In press).
Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR. Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus. BMC Genomics. 2010;11: 119. PCMID: 20167119.
Smith EC and RE Dutch. Side chain packing below the fusion peptide strongly modulates triggering of the Hendra F protein. J Virol 201084: 10928-10932. PMCID: 2950584.
Smith SH, Haas KM, Poe JC, Yanaba K, Ward CD, Migone T-S, Tedder TF. B cell homeostasis requires complementary CD22 and BLyS/BR3 survival signals. Int Immunol. 2010; 22:681-691. PMCID: 20513733.
Steele S, Buntzman A, Hensley L, Kawula T, Bixby L, and Frelinger J. Shaping the immune response to Francisella tularensis by the first infected cell J. Immunol., Apr 2010; 184: 37.33. (Abstract)
Tang H, Cao W, Kasturi SP, Ravindran R, Nakaya HI, Kundu K, Murthy N, Kepler TB, Malissen B & Pulendran B. The T helper type 2 response to cysteine proteases requires dendritic cell–basophil cooperation via ROS-mediated signaling. Nature immunology 2010;11(7):608-17. PCMID: 20495560.
Taxman DJ, Huang MT, Ting JP. Inflammasome inhibition as a pathogenic stealth mechanism. Cell Host Microbe. 2010 Jul 22;8(1):7-11. PMCID: 20638636.
Tedder TF, Matsushita T. Regulatory B cells that produce IL-10: A breath of fresh air in allergic airway disease. J Allergy Clin Immunol. 2010; 125:1125-1127. PMCID: 20451042.
Ting JP, Duncan JA, Lei Y. How the noninflammasome NLRs function in the innate immune system. Science. 2010;327(5963):286-90. PMCID: 20075243.
Torres VJ, Attia AS, Mason WJ, Hood MI, Corbin BD, Beasley FC, Anderson KL, Stauff DL, McDonald WH, Zimmerman LJ, Friedman DB, Heinrichs DE, Dunman PM, Skaar EP. Staphylococcus aureus fur regulates the expression of virulence factors that contribute to the pathogenesis of pneumonia. Infect Immun 2010;78(4): 1618-28. PCMID: 20100857.
Werden SJ, McFadden G. Pharmacological manipulation of the akt signaling pathway regulates myxoma virus replication and tropism in human cancer cells. J Virol 2010;84(7): 3287-302. PCMID: 20106927.
Wahala WM, Donaldson EF, de Alwis R, Accavitti-Loper MA, Baric RS, de Silva AM. Natural strain variation and antibody neutralization of dengue serotype 3 viruses. PLoS Pathog. 2010; 6(3): e1000821. PCMID: 20333252.
Yauch LE, Prestwood TR, May MM, Moror MM, Zellweger RM, Peters B, Sette A, Shresta S. CD4+ T cells Are Not Required for the Induction of Dengue Virus-Specific CD8+ T cell or Antibody Responses but Contribute to Protection After Vaccination. J Immunol 2010; 185:5405-5016. PCMID: 20870934.
Zellweger R M, Prestwood TR, Shresta S. Enhanced infection of liver sinusoidal endothelial cells in a mouse model of antibody-induced severe dengue disease. Cell Host Microbe 2010;7(2): 128-39. PCMID: 20153282.

2009

Since March 1, 2009 (currently funded work)

Allen IC, Scull MA, Moore CB, Holl EK, McElvania-TeKippe E, Taxman DJ, Guthrie EH, Pickles RJ, Ting JP. The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity. 2009 Apr;30(4):556-65. Epub 2009 Apr 9. PMID: 19362020
Craven RR, Gao X, Allen IC, Gris D, Bubeck Wardenburg J, McElvania-Tekippe E, Ting JP, Duncan JA. “Staphylococcus aureus alpha-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells.” PLoS One. 2009; Oct 14;4(10):e7446 PMID: 19826485
Lei Y, Moore CB, Liesman RM, O'Connor BP, Bergstralh DT, Chen ZJ, Pickles RJ, Ting JP. MAVS-mediated a poptosis and its inhibition by viral proteins. 2009; PLoS One. 2009;4(5):e5466. PMCID: 19404494.
Manicassamy S, Pulendran B. Modulation of adaptive immunity with Toll-like receptors. Semin Immunol. 2009; Aug;21(4):185-93. Epub 2009 Jun 6. PMID: 19502082.
Matsushita T, Tedder TF. Identifying regulatory B cells (B10 cells) that produce IL-10. Methods Mol BioI. 2009; (in press).
Pulendran B. Learning immunology from the yellow fever vaccine: innate immunity to systems vaccinology. Nat Rev Immunol. 2009; 9(10):741-7. PMID: 19763148.
Rahman R, Mohamed M, Kim M, Smallwood S, and McFadden G. Co-regulation of NFkB and inflammasome-mediated inflammatory responses by Myxoma virus pyrin domain-containing protein M013. Plos Pathogens 2009; 5(10):e1000635. PMID: 19851467.
Sessions OM, Barrows NJ, Souza-Neto JA, Robinson TJ, Hershey CL, Rodgers MA, Ramirez JL, Dimopoulos G, Yang PL, Pearson JL, Garcia-Blanco MA. Discovery of insect and human dengue virus host factors. Nature 2009 Apr 23;458(7241):1047-50. PMID: 19396146
Tedder TF. CD19 – A promising B cell target for rheumatoid arthritis. Nature Rev Rheum. 2009; 5:572-577. PMCID: 19798033.
Wahala WM, Kraus AA, Haymore LB, Accavitti-Loper MA, and de Silva AM. Dengue virus neutralization by human immune sera: Role of envelope protein domain III-reactive antibody. Virology. 2009; 392(1):103-13. PMID: 19631955.
Werden S, Lanchbury J, Shattuck D, Neff C, Dufford M, McFadden G. Myxoma virus M-T5 ankyrin-repeat host range protein is a novel adaptor that coordinately links the cellular signaling pathways mediated by Akt and Skp1 in virus-infected cells. J Virology 2009; 83(23):12068-83. PMID: 19776120.
Whitman SD, Smith EC, Dutch RE. Differential rates of protein folding and cellular trafficking for the Hendra virus F and G proteins: implications for F-G complex formation. J Virol. 2009; 83:8998-9001. PMCID: 19553334.
Yanaba K, Bouaziz JD, Matsushita T, Tsubata T, Tedder TF. The development and function of regulatory B cells expressing IL-10 (B10 cells) requires antigen receptor diversity and TLR signals. J Immunol. 2009 Jun 15;182(12):7459-72. PMID: 19494269
Yauch, L. E., R. M. Zellweger, M. F. Kotturi, A. Qutubuddin, J. Sidney, B. Peters, T. R. Prestwood, A. Sette, and S. Shresta. A protective role for dengue virus-specific CD8+ T cells. J Immunol 2009; 182:4865-73. PMCID: 2674070