Publications - 2009

Since March 1 (currently funded work)

Allen IC, Scull MA, Moore CB, Holl EK, McElvania-TeKippe E, Taxman DJ, Guthrie EH, Pickles RJ, Ting JP. The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity. 2009 Apr;30(4):556-65. Epub 2009 Apr 9. PMID: 19362020
Craven RR, Gao X, Allen IC, Gris D, Bubeck Wardenburg J, McElvania-Tekippe E, Ting JP, Duncan JA. “Staphylococcus aureus alpha-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells.” PLoS One. 2009; Oct 14;4(10):e7446 PMID: 19826485
Kehl-Fie TE, Skaar EP. Nutritional immunity beyond iron: a role for manganese and zinc. Curr Opin Chem Biol 2009 (In press).
Lei Y, Moore CB, Liesman RM, O'Connor BP, Bergstralh DT, Chen ZJ, Pickles RJ, Ting JP. MAVS-mediated a poptosis and its inhibition by viral proteins. 2009; PLoS One. 2009;4(5):e5466. PMCID: 19404494.
Manicassamy S, Pulendran B. Modulation of adaptive immunity with Toll-like receptors. Semin Immunol. 2009; Aug;21(4):185-93. Epub 2009 Jun 6. PMID: 19502082.
Matsushita T, Tedder TF. Identifying regulatory B cells (B10 cells) that produce IL-10. Methods Mol BioI. 2009; (in press).
OiLillo OJ, Matsushita T, Tedder TF. B10 and regulatory B cells balance immune responses during inflammation, autoimmunity and cancer. In: The Year in Immunology. Annals New York Acad Sci. 2009: (in press).
Pulendran B. Learning immunology from the yellow fever vaccine: innate immunity to systems vaccinology. Nat Rev Immunol. 2009; 9(10):741-7. PMID: 19763148.
Rahman R, Mohamed M, Kim M, Smallwood S, and McFadden G. Co-regulation of NFkB and inflammasome-mediated inflammatory responses by Myxoma virus pyrin domain-containing protein M013. Plos Pathogens 2009; 5(10):e1000635. PMID: 19851467.
Sessions OM, Barrows NJ, Souza-Neto JA, Robinson TJ, Hershey CL, Rodgers MA, Ramirez JL, Dimopoulos G, Yang PL, Pearson JL, Garcia-Blanco MA. Discovery of insect and human dengue virus host factors. Nature 2009 Apr 23;458(7241):1047-50. PMID: 19396146
Tedder TF. CD19 – A promising B cell target for rheumatoid arthritis. Nature Rev Rheum. 2009; 5:572-577. PMCID: 19798033.
Wahala WM, Kraus AA, Haymore LB, Accavitti-Loper MA, and de Silva AM. Dengue virus neutralization by human immune sera: Role of envelope protein domain III-reactive antibody. Virology. 2009; 392(1):103-13. PMID: 19631955.
Werden S, Lanchbury J, Shattuck D, Neff C, Dufford M, McFadden G. Myxoma virus M-T5 ankyrin-repeat host range protein is a novel adaptor that coordinately links the cellular signaling pathways mediated by Akt and Skp1 in virus-infected cells. J Virology 2009; 83(23):12068-83. PMID: 19776120.
Whitman SD, Smith EC, Dutch RE. Differential rates of protein folding and cellular trafficking for the Hendra virus F and G proteins: implications for F-G complex formation. J Virol. 2009; 83:8998-9001. PMCID: 19553334.
Yanaba K, Bouaziz JD, Matsushita T, Tsubata T, Tedder TF. The development and function of regulatory B cells expressing IL-10 (B10 cells) requires antigen receptor diversity and TLR signals. J Immunol. 2009 Jun 15;182(12):7459-72. PMID: 19494269
Yauch, L. E., R. M. Zellweger, M. F. Kotturi, A. Qutubuddin, J. Sidney, B. Peters, T. R. Prestwood, A. Sette, and S. Shresta. A protective role for dengue virus-specific CD8+ T cells. J Immunol 2009; 182:4865-73. PMCID: 2674070

Work funded in previous RCE grant cycle (09/01/2003-02/28/2009)

Chakraborty R, Pulendran B. Restraining order for dendritic cells: all quiet on the fetal front. J Clin Invest. 2009 Jul;119(7):1854-7. PMID: 19603541
Chamberlain AT, Burnett LC, King JP, Whitney ES, Kaufman SG, Berkelman RL. Biosafety training and incident-reporting practices in the United States: a 2008 survey of biosafety professionals. Applied Biosafety 2009; 14(3):135-143.
Hall JD, Kurtz SL, Rigel NW, Gunn BM, Taft-Benz S, Morrison JP, Fong AM, Patel DD, Braunstein M, Kawula TH. The impact of chemokine receptor CX3CR1 deficiency during respiratory infections with Mycobacterium tuberculosis or Francisella tularensis. Clin Exp Immunol. 2009 May;156(2):278-84. Epub 2009 Feb 10. PMID: 19250281
Holland DP, Sanders GD, Hamilton CD, and Stout JE. Costs and cost effectiveness of four treatment regimens for latent tuberculosis infection. Am J Respir Crit Care Med. 2009 Jun 1;179(11):1055-60. Epub 2009 Mar 19. PMID: 19299495
Huang MT, Taxman DJ, Holley-Guthrie EA, Moore CB, Willingham SB, Madden V, Parsons RK, Featherstone GL, Arnold RR, O'Connor BP, Ting JP. Critical role of apoptotic speck protein containing a caspase recruitment domain (ASC) and NLRP3 in causing necrosis and ASC speck formation induced by Porphyromonas gingivalis in human cells. J Immunol 2009; 182(40): 2395-404. PMCID: 19201894.
Kern ER, Prichard MN, Quenelle DC, Keith KA, Tiwari KN, Maddry JA, Secrist JA 3rd. Activities of certain 5-substituted 4'-thiopyrimidine nucleosides against orthopoxvirus infections. Antimicrob Agents Chemother 2009; 53(2):572-9. PMCID: 19029322.
Lan S, McLay Schelde L, Wang J, Kumar N, Ly H, Liang Y. Development of infectious clones for virulent and avirulent pichinde viruses: a model virus to study arenavirus-induced hemorrhagic fevers. J Virol. 2009 Jul;83(13):6357-62. Epub 2009 Apr 22. PMID: 19386714
Manicassamy S and Pulendran B. Retinoic acid dependent regulation of T helper cell differentiation by antigen-presenting cells. Seminars in Immunology 2008; 21(1):22-27. PMCID: 18778953.
Manicassamy S, Ravindran R, Deng J, Oluoch H, Denning TL, Kasturi SP, Rosenthal KM, Evavold BD, Pulendran B. Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity. Nat Med. 2009 Apr;15(4):401-9. Epub 2009 Mar 1. PMID: 19252500
Perry ST, Prestwood TR, Lada SM, Benedict CA, Shresta S. Cardif-mediated signaling controls the initial innate response to dengue virus in vivo. J Virol. 2009 Aug;83(16):8276-81. Epub 2009 Jun 3. PMID: 19494017.
Querec TD, Akondy RS, Lee EK, Cao W, Nakaya HI, Teuwen D, Pirani A, Gernert K, Deng J, Marzolf B, Kennedy K, Wu H, Bennouna S, Oluoch H, Miller J, Vencio RZ, Mulligan M, Aderem A, Ahmed R, Pulendran B. Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans. Nat Immunol 2009; 10(1):116-25. PMCID: 19029902.
Rehm KE, Connor RF, Jones GBJ, Yimbu K, Mannie MD, Roper RL. Vaccinia virus decreases MHC II-restricted antigen presentation, T cell activation and subsequent cytokine production. Immunol. 2009 (In press).
Sadagopal S, Braunstein M, Hager CC, Wei J, Daniel AK, Bochan MR, Crozier I, Smith NE, Gates HO, Barnett L, Van Kaer L, Price JO, Blackwell TS, Kalams SA, Kernodle DS.Reducing the activity and secretion of microbial antioxidants enhances the immunogenicity of BCG. PLoS ONE. 2009;4(5):e5531. Epub 2009 May 13. PMID: 19436730
Schäfer A, Whitmore AC, Konopka JL, Johnston RE. Replicon particles of Venezuelan equine encephalitis virus as a reductionist murine model for encephalitis. J Virol. 2009 May;83(9):4275-86. Epub 2009 Feb 18. PMID: 19225006
Sun Y, Carrion R Jr, Ye L, Wen Z, Ro YT, Brasky K, Ticer AE, Schwegler EE, Patterson JL, Compans RW, Yang C. Protection against lethal challenge by Ebola virus-like particles produced in insect cells. Virology 2009; 383(1):12-21. PMCID: 18986663.
Tang Z, Parekh P, Turner P, Moyer RW, Tan W. Generating aptamers for recognition of virus-infected cells. Clin Chem. 2009 Apr;55(4):813-22. Epub 2009 Feb 26. PMID: 19246617
Valentino MD, Hensley LL, Skrombolas D, McPherson PL, Woolard MD, Kawula TH, Frelinger JA, Frelinger JG. Identification of a dominant CD4 T cell epitope in the membrane lipoprotein Tul4 from Francisella tularensis LVS. Mol Immunol. 2009 May;46(8-9):1830-8. Epub 2009 Feb 23. PMID: 19233475